Chronic Postsurgical Pain

Epidemiology of Chronic Postsurgical Pain

Chronic postsurgical pain has a global incidence of 30 %, while surgery is the second commonest cause of neuropathic pain. The operations most commonly implicated in chronic postsurgical pain are inguinal hernia repair, breast surgery, amputation, cholecystectomy and thoracotomy. Possible risk factors are the existence of preoperative pain, psychological characteristics of the patient, certain ...

Chronic Postsurgical Pain: Definition, Impact, and Prevention

Chronic postsurgical pain: still a neglected topic?

BACKGROUND Surgical injury can frequently lead to chronic pain. Despite the obvious importance of this problem, the first publications on chronic pain after surgery as a general topic appeared only a decade ago. This study tests the hypothesis that chronic postsurgical pain was, and still is, represented insufficiently. METHODS We analyzed the presentation of this topic in journal articles co...

Chronic spinal infusion of loperamide alleviates postsurgical pain in rats.

Plantar incision in rat generates spontaneous pain behaviour. The opioid drug, morphine used to treat postsurgical pain produces tolerance after long-term administration. Loperamide, a potent mu-opioid agonist, has documented analgesic action in various pain conditions. However, loperamide analgesia and associated tolerance following continuous spinal administration in postsurgical pain has not...

Risk stratification for the development of chronic postsurgical pain

Risk stratification for the development chronic postsurgical pain is an important tool, which may permit preventive measures or appropriate advice for patients at high risk.